Black family, healthcare and a pediatrician talking to a patient in the hospital for medical child care. Kids, trust or medicine and a nurse consulting a boy with his mother in the clinic for health.

Who We Are

The Children’s Oncology Group is a research network focused on improving outcomes for children, adolescents, and young adults with cancer.

We bring together more than 220 hospitals and more than 13,500 researchers, clinicians, and specialists. Together, we work as one connected system.

We design clinical trials, lead research studies, and develop the evidence that guides treatment.

Our work does not replace care—it strengthens it.

The research we lead helps doctors use the most up-to-date treatments for children.

years of research moving childhood cancer forward, with more to learn

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    COG Member Institutions

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    Pediatric Cancer Experts

Our mission is to cure and prevent childhood and adolescent cancer through scientific discovery and compassionate care.

How Progress Happens

Progress in childhood cancer takes time, scale, and teamwork.

Because these cancers are rare, researchers must study many patients across many hospitals. COG makes that possible.

Through our network:

  • Doctors and researchers work together across hospitals
  • Clinical trials answer the most important questions in care
  • Data is shared so new knowledge can be used quickly

Each study builds on the last.

What we learn helps improve how children are treated.

Transforming What a Diagnosis Means

COG’s work has changed what a childhood cancer diagnosis means.

Decades ago, survival was rare. Today, more than 86% of children survive at least five years after diagnosis- yet too many families still face loss.

But survival is not the only goal.

Children who survive cancer have many years ahead of them. Our research looks at long-term health, side effects, and quality of life—so children can grow, learn, and live full lives after treatment.

Why It Matters

Every data point represents a child. What is learned from one child can help many others. Every study reflects the trust families place in research.

This shared knowledge helps doctors make better decisions. It leads to more consistent, informed care for children—no matter where they are treated.

Looking Ahead

There is still more to learn.

Some cancers are still hard to treat. Many children need better options.

COG continues to lead research that improves care, strengthens outcomes, and expands what is possible for children with cancer.

Each study moves us forward—step by step.

Help Turn Findings Into Futures

Every step forward in research gives children more time—time to grow, play, and live beyond cancer.

Through collaboration, careful science, and the commitment of families and care teams, we continue to shape a future where every child has that chance.

COG Foundation

The COG Foundation helps generate the philanthropic support needed to sustain COG’s mission. Through corporate sponsorships, individual philanthropy, and strategic foundation partnerships, COG Foundation helps fund discoveries that lead to more effective treatments, better outcomes, and improved quality of life for children and adolescents with cancer.

COG Research Foundation, LLC

COG Research Foundation, LLC (“Research Foundation”) serves as the fiscal sponsor of the Children’s Oncology Group (“COG”) Program, providing the administrative and operational infrastructure necessary to support COG’s clinical trial research activities through its pediatric cancer clinical research network. The Research Foundation provides awards management, financial, human resources, contracting and information technology services while ensuring strong regulatory compliance, fiduciary stewardship, and operational accountability. For information on the COG Research Foundation, LLC please visit: https://www.cogresearchfoundation.org.