About Us

Photo courtesy of Cincinnati Children's Hospital Medical CenterThe Pediatric Early Phase-Clinical Trial Network (PEP-CTN) is comprised of 21 premier Children Oncology Group (COG) pediatric oncology programs in the country that were selected through a peer review process. The PEP-CTN builds on the strengths and accomplishments of the COG Phase 1/Pilot Consortium to effectively and efficiently conduct state-of-the-art early phase trials. The PEP-CTN will leverage collaborative interaction with COG disease committees, COG leadership, NCI leadership, and the pharmaceutical industry to prioritize and streamline the development of new, targeted therapies for children with cancer. Innovative trial design and endpoints, genomic biomarkers and other correlative studies will augment the impact of PEP-CTN trials on individual patients and drug development for childhood cancer.

The PEP-CTN successfully leverages the database infrastructure and resources of the parent COG while maintaining its own administrative and operational infrastructure to ensure rapid development, implementation and reporting of specialized and complex early phase clinical trials. The PEP-CTN has expert resources for the conduct of translational biology, pharmacokinetic, and pharmacogenetics studies, and has developed a state-of-the art infrastructure to facilitate image transfer of specialized correlative imaging studies for central review and analyses.

PEP-CTN Chair
Dr. Brenda J. Weigel, MD
University of Minnesota Medical Center-Fairview
Department of Pediatrics, Hem/Onc/BMT
420 Delaware Street, SE
MMC 366
Minneapolis, MN 55455
Tel: 612 626-5501
Fax: 612 624-3913
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

PEP-CTN Vice-Chair
Dr. Elizabeth Fox, MD
Children’s Hospital of Philadelphia
Division of Oncology
3501 Civic Center Blvd, CTRB-4016
Philadelphia, PA 19104
Tel: 267 425-3010
Fax: 267 425-0113
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

PEP-CTN Operations Data/Statistics Center
Children's Oncology Group
222 E. Huntington Drive, Suite 100
Monrovia, CA 91016
Tel: (626) 241-1500
Fax: (626) 445-4334